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What is Akkermansia muciniphila and Why Is It Important for Gut Health?

headshot of Dr. Linda Khoshaba on a white background

Dr. Khoshaba

September 18, 2024

When it comes to keeping your gut healthy, good bacteria in your body do a lot of important work. One of these is called Akkermansia muciniphila. 

You may not have heard of it before, but it's gaining attention because it helps keep your gut strong and healthy. Let's explore why this tiny bacteria matters and how you can support it in your body.

What is Akkermansia muciniphila?

The image explains that Akkermansia muciniphila is a type of gut bacteria, making up about 3-5% of healthy gut bacteria. It helps break down mucin to strengthen the gut lining. The Natural Endocrinology Specialists (NES) logo is displayed.

Akkermansia muciniphila is a type of bacteria that naturally lives in your gut. A healthy person has about 3-5% of their gut bacteria from this type. 

It helps break down a substance in your intestines called mucin, which keeps your gut lining strong. A strong gut lining is like a protective barrier that keeps harmful stuff out of your body while letting the good stuff in.

What is Akkermansia muciniphila Good For?

  • Protecting the gut barrier: Akkermansia helps create a strong gut barrier by breaking down mucin in the intestines, which keeps your gut lining healthy.
  • Managing weight and metabolism: Studies show that people with more Akkermansia have healthier metabolisms, better weight control, and improved liver function. A study showed that obese patients who took Akkermansia supplements for three months lost weight and had better liver health.
  • Blood sugar control: Akkermansia may help regulate blood sugar, lowering the risk of Type II diabetes by reducing inflammation, which can lead to insulin resistance.

How Can I Increase My Akkermansia in My Gut?

While Akkermansia isn't found directly in foods, you can help it grow in your gut by eating the right kinds of foods:

  • Eat more fiber: Foods like fruits, vegetables, and whole grains are rich in fiber, which helps Akkermansia thrive.
  • Include polyphenol-rich foods: Foods like berries, nuts, and green tea contain polyphenols that help feed the good bacteria in your gut.
  • Prebiotic foods: Prebiotics, like food for gut bacteria, can help Akkermansia grow. Foods like garlic, onions, and asparagus are great choices.

What Foods Contain Akkermansia?

The image highlights foods that contain Akkermansia, including whole grains, fruits, and vegetables. It features a visual of bacteria and a colorful assortment of fresh produce. The Natural Endocrinology Specialists (NES) logo is displayed at the top.

Akkermansia isn't found in any foods, but fiber-rich and prebiotic foods can help this bacteria grow in your gut. So, focus on foods that support overall gut health, such as:

  • Fruits and vegetables: Apples, bananas, artichokes, and leeks.
  • Whole grains: Brown rice, oatmeal, and barley.

Where is Akkermansia muciniphila Found?

Akkermansia is found naturally in the human gut, especially in the mucus lining of the intestines. This bacteria plays a critical role in keeping the gut barrier strong. If you're curious about the levels of Akkermansia in your gut, stool tests can measure your gut bacteria balance.

Who Should Not Take Akkermansia?

Right now, Akkermansia supplements are still being researched. While it shows promise, people with certain health conditions, like weakened immune systems or severe diseases, should talk to a healthcare provider before trying any new supplements

Also, studies show that too much Akkermansia might be linked to issues like Parkinson's disease and eczema, so it's important to keep everything in balance.

How Long Can I Take Akkermansia?

If Akkermansia supplements become more widely available, it's best to follow the advice of a healthcare provider on how long to take them. Research is ongoing, so experts are still learning about the long-term effects. But for now, making diet changes to support this bacteria can be a safe and sustainable way to promote gut health.

How Does Akkermansia muciniphila Work?

Akkermansia breaks down mucin in the gut, which strengthens the gut lining. Doing this helps prevent toxins and harmful particles from leaking into your body and causing inflammation. 

Less inflammation means better control of blood sugar and a healthier metabolism. This makes Akkermansia important for managing conditions like obesity, Type II diabetes, and even some heart diseases.

Health Benefits of Akkermansia muciniphila

The image highlights the health benefits of Akkermansia muciniphila, including weight control, blood sugar regulation, a strong gut barrier, lower inflammation, and better metabolism. Each benefit is accompanied by relevant images, and the Natural Endocrinology Specialists (NES) logo is displayed at the top.
  • Weight control: Helps regulate fat storage and body weight.
  • Blood sugar regulation: Supports better insulin sensitivity and blood sugar levels.
  • Stronger gut barrier: Prevents harmful substances from entering your bloodstream.
  • Lower inflammation: Helps reduce chronic inflammation that leads to many health issues.
  • Better metabolism: Improves how your body processes energy and nutrients.

What Are the Negative Effects of Akkermansia?

While Akkermansia muciniphila is generally beneficial for gut health, some research indicates that an excessive amount could lead to issues. For instance, high levels of Akkermansia have been found in patients with certain conditions like Parkinson's disease and eczema​. This suggests that too much Akkermansia in the gut may worsen or contribute to these conditions.

Additionally, Akkermansia's role in breaking down the gut's mucus layer, which is generally beneficial, could become harmful if this process happens too aggressively. In cases of overgrowth might thin the mucus barrier too much, leading to increased gut permeability (also known as "leaky gut"), allowing harmful substances to enter the bloodstream and trigger inflammation.

As supplements are still being studied, monitoring how much Akkermansia is in your gut is essential, especially if you have underlying health issues. Talking to a healthcare provider before taking Akkermansia supplements is always good.

Is Akkermansia the Best Probiotic?

Akkermansia muciniphila is often called a "next-generation probiotic" due to its promising effects on metabolic health, weight control, and inflammation​. However, it's not yet widely available as a commercial probiotic. 

Early studies suggest it can help with conditions like obesity, Type II diabetes, and gut health by improving the gut barrier and reducing inflammation.

Despite its benefits, Akkermansia may only be suitable for some, and there might be better choices for all probiotic needs. Other well-known probiotics, such as Lactobacillus and Bifidobacterium, are more established for general gut health and available in supplement form​. 

Akkermansia's specific benefits are more focused on metabolic health so that it may be best suited for people with specific conditions related to metabolism and inflammation.

Conclusion

Akkermansia muciniphila may be a small bacteria, but it plays a big role in keeping your gut healthy. It supports your overall health by strengthening the gut barrier, improving blood sugar control, and helping with weight management. 

To keep your Akkermansia levels up, focus on eating fiber-rich foods and prebiotics, and always consult a healthcare provider before considering any supplements. Gut health is the foundation of a healthy life, and Akkermansia is a key player in ensuring it stays that way!

References:

Depommier, C., Everard, A., Druart, C., Plovier, H., Van Hul, M., Vieira-Silva, S., Falony, G., Raes, J., Maiter, D., Delzenne, N. M., de Barsy, M., Loumaye, A., Hermans, M. P., Thissen, J. P., de Vos, W. M., & Cani, P. D. (2019). Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study. Nature medicine, 25(7), 1096–1103. https://doi.org/10.1038/s41591-019-0495-2

Rodrigues, V. F., Elias-Oliveira, J., Pereira, Í. S., Pereira, J. A., Barbosa, S. C., Machado, M. S. G., & Carlos, D. (2022). Akkermansia muciniphila and Gut Immune System: A Good Friendship That Attenuates Inflammatory Bowel Disease, Obesity, and Diabetes. Frontiers in immunology, 13, 934695. https://doi.org/10.3389/fimmu.2022.934695

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What is Akkermansia muciniphila and Why Is It Important for Gut Health?

When it comes to keeping your gut healthy, good bacteria in your body do a lot of important work. One of these is called Akkermansia muciniphila.  You may not have heard of it before, but it's gaining attention because it helps keep your gut strong and healthy. Let's explore why this tiny bacteria matters and […]

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Dr. Linda Khoshaba is the Leading Integrative Health and Hormone Doctor in Scottsdale, Arizona. She has extensive experience working in the field as a Hormone Specialist and Natural Endocrinologist.

Phone: 480-687-0054
Fax: 833-605-1101
Email: contact@nesaz.com
Address: 
Suite A 109
7500 E. Pinnacle Peak Rd. 
Scottsdale, AZ 85255

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